Sunday, August 19, 2012

TYPICAL COURSE OF AN AUTISTIC PATIENT


TYPICAL COURSE OF AN AUTISTIC PATIENT
By Dr. Steven Marini M.S., D.C., Ph.D.

1. Hepatitis B immunization at 12 hours after birth. DPT immunization at 4 and 8 weeks*, oral polio immunization also at 4 and 8 weeks, again at 3 months.
Schedule now being changed; children will receive 2 doses of live attenuated oral polio and 2 doses killed polio; oral polio can cause disease; only killed polio is used in Europe.
2. Because of great decrease in cell-mediated immunity (CMI) in infants, the vaccines lower CMI further; one decreases CMI by 50%; two together by 70%.
Longest safety trail of the triple vaccine (MMR, all live attenuated viruses) was three weeks.
3. Repeated immunizations with 3 vaccines simultaneously, e.g., Pneumococcus, Haemophilus, etc. from 4 weeks to 12 to 18 months. Repeat DPT is given at 12 months. * All these triple vaccines markedly impair CMI.
4. Resultant decrease in CMI predisposes to recurrent viral infections, especially otitis media, since CMI controls response to viruses (also fungi [e.g., Candida], parasites [e.g., leishmaniasis], mycobacterium [e.g., tuberculosis, even if drug resistant] and leprosy).
5. When infections occur, bacterial cultures rarely performed, yet infants repeatedly given antibiotics. Antibiotics are of absolutely no help in viral infections; in some countries, antibiotic administration without a prior culture is considered malpractice.
6. Antibiotics wipe out helpful bacteria in the gut (e.g., lactobacilli, bifidobacteria), which have important protective functions, including prevention of infection by yeast, pathogenic bacteria, and/or parasites. The protection is provided in part by the helpful bacteria clinging to the intestinal cell wall, thus preventing pathogenic microorganisms from getting to it. The pathogenic bacteria compete with the body for vitamin B-12 and perhaps other vitamins and minerals.
7. After helpful bacteria wiped out, Candida usually develops. Candida produces toxin; however, its main deleterious effect is avid binding of coenzyme q10, usually at barely adequate levels in the diet of normals to begin with, to a far greater extent than by normal tissues. Candida is not the cause of increased intestinal permeability, except in rare instances, since substances passing into the body enter via the small intestine (jejeunum) whereas Candida is almost always confined to the large intestine (but if present in jejeunum, can be life-threatening.)
8. The Candida infection is usually treated with ketoconazole or similar anti-yeast antibiotic.
9. Ketoconazole and similar compounds impair patient's liver function as shown by liver detoxification profile. This could also be a factor in increased intestinal permeability, because the liver also synthesizes the J piece (joining piece) that binds two molecules of IgA antibodies together to form secretory IgA, which protects the intestinal tract from a variety of damaging agents; severe diminution of secretory IgA predisposes to increased intestinal permeability. Furthermore, since the blood vessels from the colon go directly to the liver via the enterohepatic circulation, the various toxins from microorganisms and undigested food in the colon go directly to the liver.

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