Wednesday, January 27, 2010

Immune Health and Autoimmune Illnesses



Research indicates that EPA and DHA from cold water fish oils like Omega Sufficiency® are required for healthy immune function. Scientific evidence also indicates that a deficiency in EPA and DHA Omega 3 fatty acids can lead to altered immune function increasing the chance of autoimmune disorders such as rheumatoid arthritis, multiple sclerosis, lupus, and Crohn’s disease.

Studies in populations consuming sufficient amounts of Omega-3 fatty acids show decreased incidence of inflammatory and autoimmune diseases. Epidemiological studies like this provide even more evidence of the essential role of EPA and DHA for proper immune function and thus the prevention of autoimmune disorders and other immune function related illnesses.

Research has also shown Omega-3 fatty acid supplementation to be of significant benefit for people who have already developed autoimmune conditions such as rheumatoid arthritis, lupus, multiple sclerosis, and Crohn’s disease (see section on Digestive Health).
The scientific literature indicates that for proper immune system function and for the prevention of autoimmune conditions sufficient intake of EPA and DHA Omega 3 fatty acids as found in Omega Sufficiency® is vital. Without sufficient intake of these essential nutrients proper immune function is simply not possible.

In your Health,
Dr Jon Wise

References

Belluzzi A, Brignola C, Campieri M, et al. Effect of an enteric-coated fish-oil preparation on relapses in Crohn’s disease. N Engl J Med 1996;334:1557–60.

Cendrowski W. Multiple sclerosis and MaxEPA. Br J Clin Pract 1986;40:365–7.

Connor, W.E. Importance of n-3 fatty acids in health and disease. Am J Clin Nutr, 2000 71(1): 171S-175S

Curtis, CL, Hughes, CE, Flannery, CR, Little, CB, Harwood, JL, Caterson, B. (2000). N-3 fatty acids specifically modulate catabolic factors involved in articular cartilage degradation. Journal of Biological Chemistry, vol. 275(2), p. 721-4

Ergas, D., Eilat, E., Mendlovic, S., Sthoeger. (2002). N-3 fatty acids and the immune system in autoimmunity. Israeli Medical Association Journal, vol. 4(1), p. 34-8.
Geusens, P., Wouter, C., Nijs, J., Jiang, Y, Dequeken, J. (1994). Long-term effect of omega-3 fatty acid supplementation in active rheumatoid arthritis, a 12-month, double-blind, controlled study. Arthritis & Rheumatism, 37(6), p. 824-829.

Goldberg P, Fleming MC, Picard EH. Multiple sclerosis: decreased relapse rate through dietary supplementation with calcium, magnesium and vitamin D. Med Hypothesis 1986;21:193–200.

Kelley VE, Ferretti A, Izui S, Strom TB. A fish oil diet rich in eicosapentaenoic acid reduces cyclooxygenase metabolites, and suppresses lupus in MRL-1pr mice. J Immunol 1985;134:2914–9.

Mate J, Castanos R, Garcia-Samaniego J, Pajares JM. Does dietary fish oil maintain the remission of Crohn’s disease: a case control study. Gastroenterology 1991;100:A228 [abstract]

Simopoulos, AP. Omega-3 fatty acids in inflammation and autoimmune diseases. J Am Coll Nutr. 2002 Dec;21(6):495-505

Volker, D, Fitzgerald, P., Major, G., Garg, M. (2000). Efficacy of fish oil concentrate in the treatment of rheumatoid arthritis. Journal of Rheumatology, Oct;27(10), p. 2305-7.

Walton AJE, Snaith ML, Locniskar M, et al. Dietary fish oil and the severity of symptoms in patients with systemic lupus erythematosus. Ann Rheum Dis 1991;50:463–6.

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