Wednesday, January 27, 2010

Healthy Regulation of Inflammation and Pain



Contrary to popular belief, both inflammation and pain are healthy, necessary parts of healing from acute stress and injury. Inflammation and pain can however become chronic and “hyper” when the body is in a chronic state of imbalance or toxicity or deficiency.

Sufficiency of EPA and DHA Omega 3 EFAs plays a major role in regulating inflammation via substances called prostaglandins. EPA and DHA Omega 3 fatty acids produce anti-inflammatory prostaglandins while Omega 6 fatty acids produce pro-inflammatory prostaglandins.

Having a diet that is toxic with Omega 6 or deficient in Omega 3 EFAs creates a pro-inflammatory state within the body. This is very significant because inflammation is at the root of virtually all of the common chronic illnesses such as heart disease, stroke, diabetes, and depression as well as the autoimmune and atopic diseases such as arthritis, Crohn’s Disease, irritable bowel, psoriasis, eczema, allergies, fibromyalgia, lupus, and multiple sclerosis. Inflammation is also a major factor in dysmenorrhea (menstrual pain and/or cramping), headaches, and back and neck pain.

It is well documented that restoring Omega 3 sufficiency and restoring the proper Omega 3:Omega 6 fatty acid ratios with EPA and DHA supplementation (Omega Sufficiency®) is effective at reducing excess inflammation and the pain and illnesses associated with it.

In your Health,
Dr. Jon Wise

References

Altman R, Gray R. Inflammation in osteoarthritis. Clin Rheum Dis 1985;11:353.
Connor, W.E. Importance of n-3 fatty acids in health and disease. Am J Clin Nutr, 2000 71(1): 171S-175S

Geusens, P., Wouter, C., Nijs, J., Jiang, Y, Dequeken, J. (1994). Long-term effect of omega-3 fatty acid supplementation in active rheumatoid arthritis, a 12-month, double-blind, controlled study. Arthritis & Rheumatism, 37(6), p. 824-829.

Glueck CJ, McCarren T, Hitzemann R, et al. Amelioration of severe migraine with omega-3 fatty acids: a double-blind placebo controlled clinical trial. Am J Clin Nutr 1986;43:710 [abstr].

Harel Z, Biro FM, Kottenhahn RK, Rosenthal SL. Supplementation with omega-3 polyunsaturated fatty acids in the management of dysmenorrhea in adolescents. Am J Obstet Gynecol 1996;174:1335–8.

McCarren T, Hitzemann R, Allen C, et al. Amelioration of severe migraine by fish oil (omega-3) fatty acids. Am J Clin Nutr 1985;41:874 [abstr].

Simon, Joel A., et al. Serum fatty acids and the risk of coronary heart disease. American Journal of Epidemiology, Vol. 142(5), p. 469-76

Simopoulos, A.P. Omega-3 fatty acids in inflammation and auto-immune diseases. J Am Coll Nutr. 2002 Dec; 21 (6): 495-505

Simopoulos, AP (1997). Omega-3 fatty acids in the prevention-management of cardiovascular disease. Canadian Journal of Physiological Pharmacology, Vol. 75(3),

Volker, D, Fitzgerald, P., Major, G., Garg, M. (2000). Efficacy of fish oil concentrate in the treatment of rheumatoid arthritis. Journal of Rheumatology, Oct;27(10), p. 2305-7.

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